Abstract: Among all of the sonification research areas, multi-dimensional mapping of continuous data becomes the hotspot of current research as it is difficult to solve. Sonification research on one-dimensional data or discrete signals are currently drawing more attention than the other research areas. For the multi-dimensional signal, the choice of mapping variable should be very careful due to its need to find a suitable intermediate mapping variables. There are relatively few people involved in the in this area and hence very little literature can be found. As the research object, this study chooses the two-dimensional signal and takes medical images as example, choosing gray-scale, gradient and camber as the intermediate mapping variables, to research the sonification of two-dimensional orthopedic medical images.