Abstract: In this study, a novel Ultra-wideband (UWB) bandpass filter with single notched band based Microstrip line and Coplanar Waveguide (CPW) Hybrid Structure is presented which can effectively restrain the electromagnetic interference between systems, to ensure immunity of the system. The proposed filter is based on microstrip-fed CPW resonant structure, among which, two identical structure microstrip feeder and open-ended coplanar waveguide are located in the upper and lower layers of the dielectric substrate. The Complementary Split-Ring Resonators is embedded on the lower structure in the middle of a length of approximately 1/2 wavelength CPW which gets the adjustable notch band, thereby gaining the dual band. Experiment results demonstrated that the bandwidth of filter designed is from 3.1 to 10.6 GHz (-3 dB bandwidth), fractional bandwidth of 92% at the central frequency 6.8 GHz and the notch band can be changed optionally from 3.6 to 9 GHz.