Abstract: An empirical model based on five factors of consumers cultural differences in TV home shopping is presented to predict the development of TV home shopping in this study. We have used the model to calculate the MOTHSD of 74 countries and regions. The results suggest that the higher MOTHSD of a country is, the faster development TV home shopping gets in the country. We have collected the data about TV home shopping in the three representative countries such as USA, UK and China to testify our model. The facts and practical figures are compatible with the results, which prove that the results got from the model are correct and our model is practical. The empirical model has the descriptive power on TV home shopping and our research can also provide a framework for management in electronic home shopping market.