Abstract: Since turkeys are in continuous contact with the litter, the potential effects of bedding materials and their quality are of major concern in the etiology of Foot Pad Dermatitis (FPD). Two week-old female turkeys were allotted to four groups, with 29 in each and housed either on wood shavings, lignocellulose, chopped straw or dried maize silage over a period of four weeks without artificial climatisation. The birds in all groups were fed identical commercial diets. Half of the turkeys in each group were additionally exposed for 8 h/d to corresponding wet (27% DM; by adding water) litter in adjacent separate boxes. Foot pads of the birds were examined macroscopically and histologically at the start and end of the experiment as well as at weekly intervals. Lignocellulose showed the lowest severity of FPD on dry and wet litter treatments, whereas chopped straw was associated with high FPD scores on dry treatment. Foot pad scores were similar on wood shavings and dried maize silage whether dry or wet. The DM content of litter materials was determined and the highest moisture content among dry treatments was observed in straw (about 31%) which was paralleled with FPD severity. The severity of FPD was overall much higher (>2 times) on wet than on dry litter. Exposure of the birds to wet litter for 8 h/d was sufficient to develop FPD. Lignocellulose could reduce the FPD severity, probably due to higher water binding capacity and faster release of water, while straw may increase it due to lower water evaporation. The physical form of litter either soft (lignocellulose) or with sharp edges (chopped straw) may also affect the onset of FPD. The litter moisture appears to be the dominant factor resulting in the development of FPD and should be kept lower than about 30% to minimise the prevalence and severity of FPD in turkeys.