Abstract: A study was conducted to determine the effect of commercial enzyme (Natugrain) supplementation on the nutritive value and inclusion rate of guar meal in broiler rations. Eight isocaloric and isonitrogenous starter rations were prepared having ME 2800 Kcal/kg and CP 20%. In similar way 8 isocaloric and isonitrogenous finisher rations were prepared having ME 2900 Kcal/kg and CP 19%. 240 one day old broilers were divided into two groups I and II. Group I was further divided into 4 sub groups A, B, C and D which were fed enzyme supplemented rations containing 0, 5, 10 and 15% guar meal, respectively. The dose of enzyme was 100 gram/ton of feed. Group II was also divided into 4 sub groups E, F, G and H which were fed rations without enzyme supplementation containing 0, 5, 10 and 15% guar meal, respectively. Each sub group had 30 chicks, 3 replicates of 10 chicks. For groups A, B, C, D, E, F, G and H average values of feed consumption were 3631.2, 3797.16, 3601.0, 3086.56, 3664.33, 3736.2, 3604.93 and 3254.83 grams, average values of weight gain were 1817.77, 1813.6, 1648.77, 1169.0, 1796.1, 1723.9, 1538.44 and 1265.9 grams, average values for FCR were 1.97, 2.0, 2.17, 2.64, 1.99, 2.14, 2.33 and 2.56, values of dressing percentage were 67.5, 64.13, 64.07, 61.73, 66.20, 63.33, 63.70 and 61.33%, cost per kg live weight gain was Rs. 25.94, 26.82, 28.27, 35.36, 26.16, 27.65, 29.98 and 33.69, respectively and mortality percentage in these groups was 3.33, 0, 0, 13.33, 3.33, 0, 3.33 and 6.66%, respectively. It was concluded that guar meal reduced weight gain, dressing percentage of chicks and deteriorates FCR. Furthermore, addition of enzyme did not result in significant improvement in feed consumption, weight gain, FCR and dressing percentage, however economics was improved with enzyme addition but 15% guar meal with enzyme prove to be least efficient.