Abstract: A total of 3747 cases were assessed to understand the prostrate cancer profile in the population of West Bengal from 2003-2010. Present investigation revealed that prostate cancer rate was climbing with 5.71% incidence and the ignorance is partially responsible for that alarmingly high incidence in elder males particularly from 51-70 years age group. The level of PSA (Prostate Specific Antigen) in the blood was high (<4 ng mL-1) in men having prostate cancer. The cancer frequency was moderate during 2003 to 2006, but it rises drastically from 2007 (17.76%) and reached maximum peak (28.97%) in 2010. Prostate cancer was most prevalent in group A, followed by group B and group O. The absolute number of new cancer cases was increasing rapidly, due to growth in size of the population and increase in the proportion of elderly persons as a result of improved life expectancy. The risk of developing prostate cancer was related to age, genetics, race, diet, lifestyle, medications and other factors. This peak cancer scenario can be altered in a positive direction by regular screening and by training the prevention measures of life style modification in a wide scale through proper way.