Abstract: A disease complex involving Meloidogyne incognita and Fusarium solani was studied on tomato (Lycopersicon esculentum, Mill.) under glasshouse conditions. Pot experiments were conducted to determine the pathogenesis of both the pathogens individually, simultaneously and sequentially. Isolates of M. incognita and F. solani singly caused a significant reduction in plant height, fresh weight, dry weight, number of fruits and fruit weight over the un-inoculated one but the reduction was more by M. incognita as compared to F. solani. A significant reduction in different plant growth parameters was observed on simultaneous and sequential inoculation of M. incognita and F. solani. However, the reduction was more prominent on simultaneous inoculation of both the pathogens. Among the sequential inoculations more damages were assessed during inoculation of M. incognita followed by F. solani (N+f10). Nematode multiplication, number of galls and number of females were adversely affected on simultaneous and sequential inoculation of both the pathogens in all the treatments. In the present study it was concluded that both the pathogens viz M. incognita and F. solani are virulent against the tomato c.v pusa ruby and therefore measures to prevent the spread of disease become important.