Abstract: Background and Objective: Agriculture is the largest food producing sector of the economy of Bangladesh. It is essential to adopt more steps for increasing the production level of rice. Fertilizers are inevitable for the crop production systems of modern agriculture. Among the factors that affect crop production, fertilizer is the most significant factor that plays a crucial role in yield increase. The experiment was conducted to observe the effect of fertilizer and agronomic management on growth, yield and yield contributes of boro rice. Materials and Methods: The experimental site was located under the Agroecological Region Sylhet Basin (AEZ-21) having moderately acidic soils. The experiment was designed with seven treatments including T1: Farmers’ practiced based fertilizer (180-42-42 kg ha–1 of urea-TSP-MoP), T2: BARC recommended dose based fertilizer (300-112-127-75-11 kg ha–1 of urea-TSP-MoP-CaSO4-ZnSO4), T3: T2+Wet Irrigation, T4: T2+Wet and dry irrigation, T5: T2+Proper seedling age, T6: T2+PSA (proper seedling age), T7: IPNS (integrated plant nutrient system)+proper seedling age+IPM. The test crop was BRRI dhan58. The experiment was laid out in a randomized complete block design (RCBD) with five farmers’ replications. Data were taken on growth, yield and yield contributing characters of BRRI dhan58 and analysed with the help of MSTAT-C program. Results: The plant height varied significantly and found the longest plants due to T7. Tillering followed the similar pattern of plant height where the highest number of tillers hill–1 were recorded in T7 IPNS (integrated plant nutrient system)+proper seedling age and spacing+IPM. The yield and yield contributing characters of BRRI dhan58 varied significantly due to application of balanced fertilizers according to BARC recommendation guide with proper agronomic management. The highest grain yield (8.74 t ha–1) and straw yield (11.77 t ha–1) were recorded from IPNS (integrated plant nutrient system)+proper seedling age and spacing+IPM over farmers’ practice based fertilizers (T1). Post-harvest soils showed the higher nutrient content in comparison to initial soil due to application of balanced fertilizers. Conclusion: It was concluded that balanced fertilizer application with proper agronomic management may be recommended for higher yield of BRRI dhan58 in the hoar area.