Abstract: In this research, the influence of infra-red laser on four wheat cultivars from Kazakhstan and Egypt were carried out in order to enhance their germination percentage. Seeds were in vitro irradiated to IR laser for 0, 1, 3, 10, 30, 60, 180, 600, 1200 and 1800 sec. Seeds pre-sowing irradiation with monochromatic infra-red (IR) laser have increased the germination percentage of the four wheat cultivars. Maximum germination percentages noticed were mainly after IR-seed pre-sowing irradiation with 1, 60 and 1200 sec. Generally, IR laser enhanced the germination percentage of wheat cultivars after 3 days to reach a maximum of 93.3%3 in cultivar akcay after irradiation for 1200 sec. An IR-irradiation of 30 sec caused a general inhibition in germination in the four studied cultivars with minimum germination percentage of 6.7%3 recorded in sakha-168. Germination percentage at 5 and 7 days showed a similar behavior with maximum germination percentage recorded mainly at 30 sec of infra-red seed irradiation. So, seed pre-sowing irradiation with IR laser one-shot for 1 sec is recommended to be enough to enhance the germination percentage of experimented wheat studied.