Abstract: Background and Objective: The study of zooplankton composition, abundance and seasonal variations is helpful in planning and successful fishery management, therefore this study attempts to shed light on the current state of the zooplankton community of this creek given its present poor state of knowledge. Materials and Methods: The zooplankton assemblage structure and distribution in Stubbs Creek, Akwa-Ibom state, Nigeria was studied (September, 2011-August, 2013). Three sampling stations were chosen. Samples were obtained by filtering 100 L of water through standard plankton net with a base collector of 500 mL. The samples were preserved in 5% formalin. Identification and counting of zooplankton was done using Zeis inverted microscope and identification keys. Results: A total of 9 species belonging to 6 taxonomic groups were recorded. The class Maxillopoda was the most abundant in number and species. Maxillopoda made up 50% of the total zooplankton identified, followed by Appendicularia with 22%. Other classes consisted of <10% each of the total zooplankton. Only Maxillopoda had 4 species, the other classes had 1 species each. The low zooplankton diversity observed in this study is common in tropical waters. Calanoida copepod was the most dominant (27.27%) zooplankton taxa, followed by Oikopleura (22.73%). The dominance of copepods in this creek makes it a good breeding ground for most fish fauna. Although there were differences in the abundance of the zooplankton taxa with seasons, they were not statistically different (p>0.05). The highest number of zooplankton taxa (6) was observed in station 1 while the highest number of zooplankton individuals (180) was observed in station 2. Stations 3 recorded the lowest zooplankton taxa of 4. The dominance of copepods may have accounted for the low Margalef species diversity (<1.012) and low Shannon-wiener index (<1.748) recorded during the study. Conclusion: It is agreed by pollution biologist that species diversity declines as pollution effects are more severe. Stubbs creek is environmentally stressed and this requires urgent monitoring of the activities on this creek to maintain a sustainable, productive and healthy ecosystem.