Abstract: A polyester/cotton blended fabric of 2 blending ratios is printed with a single class of dye (nano disperse dye) via 2 burn-out techniques. Burn-out effect is accomplished in the present work through using 2 acids separately: Nitric and sulfuric acids. The first technique involves printing the substrates with a paste that contains the nano disperse dye refluxed in nitric acid. In the second technique, the fabric is printed with a burn-out agent (sulfuric acid) followed by overprinting with the milled disperse dye treated with ultrasound waves. All parameters found to affect the K/S values as well as percentage of weight loss of the printed blended substrates are investigated in detail. Results show that the use of single class of dye nanoparticles enormously improves the colour depth of the prints also best burn-out effect can be obtained using sulfuric acid (with reasonable weight reduction).