Abstract: The objective of this study was to incorporate the control and management of infertility within the framework of maternal and child health and family planning program in primary health care setting. It was a cohort study and was held in central of Sudan, from June 2007 to June 2009. It was conducted in four health centers. Sample size was 200 infertile couples, selected by taking 10% from total number of all married female patients visited primary health care center complaining from any health problem during one month. Data were collected by special questionnaire includes, demographic data, medical history and examination, investigations and management. Data collection was performed by the author, doctor, midwife and nurse of each health centre. Investigations were done within the laboratory of health centers which include; blood test, urine analysis, seminal analysis, hormonal assay, high vaginal swap for culture and sensitivity, histosalpingiography and ultra sounds were done in the central laboratory. Outcome results were; 80% had primary infertility and 20% had secondary infertility. Infertility due to husbands alone was 20.5%, that due to wives alone was 37.5% and infertility due to both couple was 31% while those with unknown aetiology was 11%. The main cause of female primary infertility was unovulatory cycle and for secondary infertility were tubal problems. Male infertility due to seminal abnormality was 42.5% and those with medical problem was 2%. Management varied from health education, hormonal therapy, antibiotic and surgical intervention. By the end of the first year, 52 women got pregnant. Outcome was 48 well new born babies.