Abstract: Gender concerns militate against the extension of equal opportunities to women and children and therefore, lead to frustration, apathy, violence and lop-sided development and underdevelopment. Considering the unsung role women and children play in development and the need to operationalise equal opportunities for the enhancement of sustainable human development, this paper examines the various practices of marginalization of women and children in Nigeria. Based on interview conducted among women and children and evidence from key informant sources, the study identifies unemployment, inadequate health facilities, rights and disinheritance issues, suppressed status, child trafficking/labour/prostitution, poor representation in governance, underdevelopment and inadequate access to microcredit as some areas of marginalization against women and children. Recommendations on addressing the situation were made.