Abstract: Azadirachta indica A. Juss. (neem) is a source of several bioactive components, however only Azadirachtins have been commercially exploited. A quantitative HPLC analysis of the components present in an aqueous extract of powdered neem leaves prepared in the traditional manner was undertaken. This study indicate that aqueous extracts contain Azadirachtin A, B, D, H, I, Desacetylnimbin, Azadiradione, Nimbin, Salanin, Azadirone, Nimbolin, Nimbinene, Nimbolide. Neem leaves extract have been used for pesticide, fertilizer, corrosion inhibition and biosorbent for dyes.