Abstract: Current study was designed to explore the effect of poor quality water on rice growth and yield under saline paddy soil of Egypt. Two field experiments were conducted at agriculture research station of El-Sirw, Damitta province, Egypt during the years 2003 and 2004. The water quality treatments were; Mixed water (MW) with salinity level of 1.9-1.92 dS m-1 used from seedling to harvesting (T1), drainage water (DW) with 4.69-5.2 dS m-1 up to harvesting (T2), MW up to panicle initiation (PI) + DW up to harvesting (T3) and DW up to PI + MW up to harvesting (T4). The ponded water depth treatments were saturation (0 cm), 3 and 6 cm water depth and watering was done after every 4 days. Rice growth and yield was significantly affected by both water quality treatments and pond depths. The Leaf Area Index (LAI), Dry Matter (DM) and number of tillers increased as flooding depths were increased and submergence level of 6 cm depth gave greater LAI, DM and number of tillers. While, crop growth under mixed water treatment was better regarding LAI, DM, number of tillers m-2 and days to flowering. Yield components were increased with increasing the ponding depth up to 6 cm except sterility%. Mixed water treatment had favorable affect on yield components, while number of panicle reduced by 14.1, 5.8 and 6.3% and filled grains reduced by 29.7, 7.7 and 24.1% in T2, T3 and T4, respectively. It was observed that Ca2+ and K+ contents in rice leaves increased with ponding depth but Na+ contents reduced. While Na+ uptake was lower in MW treatment (T1) than Ca2+ and K+ uptake as compared to other treatments. Current study suggests the use of MW at early growth stage and its substation by DW at late growth stage for rice growth under saline soil condition. Analogously, flooding depth with 6 cm is recommended to apply when poor quality water has to be used in the irrigation under saline soil.