Abstract: This research was conducted in the 1998 and 1999 main crop season in the Southeastern Anatolia Region of Turkey. The experimental design was a Completely Randomized Block with three replications. In the research, were used 24 grain Sorghum cultivars to determine high yielding cultivars. The grain yields of the grain sorghum cultivars varied between 3589.9-9634.8 kg ha-1 in the research. In all the observed characters, statistically significant differences were determined among cultivars. The positive and significant relationships were determined between the grain yields and grain yields per panicle, panicle lengths, plant heights (p<0.01). However, the negative and significant relationships were determined between the crude protein percentages and grain yields, panicle lengths, 1000 seed weights (p<0.01). As a result, DK 64 and KS 989 were determined as high yielding cultivars under Southeastern Anatolia Region conditions as main crops season.