Abstract: A synthetic insecticide (Monocrotophos 40WSL) and three botanical infusions (Datura alba Seed Extract Infusion, SEI; Calotropis procera Latex Infusion, LI and Citrullus colocynthus Fruit Extract Infusion, FEI) were tried against onion thrips on broadcasted onion variety “Chlitan 89” in Quetta, Pakistan. All tested insecticides caused mortality of onion thrips at various degrees of significance over untreated control. C. procera LI, proved it self the best among the tested botanical insecticides and provided 42.67 % control after Monocrotophos that caused 76.24 % mortality of onion thrips. D. alba SEI and C. colocynthus FEI showed minimal control (17.23 and 6.77 % respectively) of the said pest than other tested insecticides but the results encourage the idea of pollution free methods of pest control. The C. procera LI can be used as good as any other botanical insecticide in Integrated Pest Management (IPM) of onion thrips.