Abstract: A field experiment was conducted during 2000-01, to investigate the effectiveness of different herbicides for controlling weeds in wheat. Significant differences were observed among the times of application for weed density after herbicidal treatments and number of tillers plant-1. Similarly significant differences were recorded for herbicidal treatments in the traits like weed density after herbicidal application and number of tillers plant-1. The interactions of times of application and herbicides were significant for weeds density after herbicidal application and number of tillers plant-1. The 45 DAS herbicidal application time was best for tillers plant-1. As a whole the herbicidal application at 45 DAS provided excellent weed control. Weeds were most effectively controlled by buctril-M + topik, isoproturon alone and logran + topik. None of the herbicides except isoproturon 75 WP at 30 DAS application had a phytotoxic effect on the wheat crop. Highest number of tillers plant-1, were produced by buctril-M + topik and logran + topik as compared to weedy check.