Abstract: Background and Objective: With the completion of the Arabidopsis genome sequencing, the next challenge is the determination of gene function. Post-translational modifications of proteins by small polypeptide are implicated in plant growth and development. Ubiquitin fold modifier 1 is a member of the ubiquitin like protein family. While, the enzymatic conjugation cascade of ubiquitin fold modifier 1 has been elucidated in recent years, its biological role is still unknown. The present study focuses in elucidate the role of the ufm1 in plants development. Materials and Methods: The researchers performed analyses of the development of wild-type Columbia plants and mutants of the ubiquitin fold modifier 1 gene to identify and interpret phenotypic changes in plants and seeds. Data were statistically analyzed with the Info Stat software. Results: In this study, evidence suggesting that ubiquitin fold modifier 1 is involved in the normal development of the seeds. Conclusion: The ufm1 gene would affect the normal development of the seed, particularly of the embryo, causing high percentage of seed abortion.