Abstract: The search for increased productivity of common bean in Upper Katanga by controlling weed justified the study conducted on the site of Institut National Pour l’Etude et la Recherche Agronomiques (INERA, Kipopo) to Kaniameshi during the 2014-2015 cultural season. The test was carried according to a split-plot arrangement with three repetitions. Varieties constituted the main factor CODMLB001, RCB262, HM21-7 and CODMLB007 while in manual weeding; 30 and 60 DAS, unweeding and chemical weeding (3 L ha–1 Paraquat+3 L ha–1 Atrazine) spread 10 days before seedling were the secondary factor. The results showed a positive varietal effect of CODMLB007 on the yield (0.43 t ha–1). Managements modes strongly influenced all the observed parameters, but the high seed yield (0.55 t ha–1) was performed in row plots manually, against a slight gap (0.51 t ha–1) to the chemically treated plots and finally a large gap (0.04 t ha–1) for unweeded plots. No any interaction was observed for yield after combination of two factors. Furthermore, the adventitious flora was dominated by the Cyperus rotundus species common to all plots with a max relative frequency (12). This could be explained by biology, the action of management methods and the long monoculture, however, the active matter were applied had a short persistence period in soil. Manual weeding induced awakening dormant buds or by splitting tubers or suppression of stripping, C. rotundus competitor had a high impact opposite the culture and other weeds. Therefore, it would be interesting to advocate a selective post-emergence treatment catching up or combine manual weeding treatment before seedling.