Abstract: A premix, containing different proportion of locally available ingredients namely wheat, bengal gram, dried peas, defatted soyflour, barley and fenugreek seeds, was administered to 30 NIDDM subjects, equal number of both sexes to find out the impact of administering indigenous fibre rich therapeutic premix on blood glucose levels. The study was conducted in Amritsar city, India. The premix was given during breakfast in the form of chapattis for 90 days without disturbing the daily dietary pattern of the selected diabetic subjects. The study revealed that there was a significant reduction in fasting and post prandial blood glucose levels after 90 days of the premix supplementation. After the premix supplementation, the dose of oral hypoglycaemic drug was also reduced. All the subjects reported that there was decrease in the diabetic symptoms experienced by them at the end of the period of premix supplementation. The study thus indicated that the blood glucose level in diabetic patients could be reduced efficiently and gradually through the daily intake of less expensive premix, which can be easily prepared at home.