Abstract: Background and Objectives: Children with underweight have a greater risk of having common infection. The frequency and severity of the infection increase and contribute to delayed recovery. This study aimed to assess the golden standard feeding practice as a risk factors of underweight Children aged 25-60 months in Central Sulawesi, Indonesia. Materials and Methods: This study uses analytical survey with case control approach. The sample in this research involved 33 cases and 66 controls of the same age and gender. Univariate and multivariate logistic regression analyses were conducted. Crude odds ratio and adjusted odds ratio with 95% confidence interval were analyzed. Results: Logistic regression analyses revealed that not practising early initiation of breastfeeding (Odds ratio = 5.56, 95% confidence interval = 1.70-18.15), inappropriate complementary feeding (Odds ratio = 6.09, 95% confidence interval = 1,32-28.06), less varied complementary food (Odds ratio = 9.81, 95% confidence interval = 2.62-36.68) were associated with underweight, while exclusive breast feeding (Odds ratio = 0.75, 95% confidence interval = 0.15-3.64) and breast feeding up to 2 years old (OR = 0.85, 95% CI = 0.24-3.02) were not associated with underweight. Conclusion: The golden feeding standard of babies and young children which includes early initiation of breastfeeding, appropriate complementary food, variation of complementary feeding. However, it excludes exclusive breastfeeding and breastfeeding up to 2 years or beyond are the protective risk of underweight in Palu, Indonesia.