Abstract: Background and Objective: Palm oil wastes generated manually and mechanically pose a serious environmental problem in Nigeria. Most of these wastes are indiscriminately discarded into the environment with little or no treatment. This practice is an environmental concern which needs to be addressed. Alternative economic disposal methods are necessary and one potential method is to test for the effects of these wastes plants. This paper describes a study in which palm oil wastes soil was assessed for its effects on the growth and phytochemical constituents of Amaranthus hybridus. Materials and Methods: Soil samples polluted with palm oil wastes was collected in polythene bags from a palm oil wastes dumpsites at Ogodo, Ankpa local government area of Kogi state, Nigeria at a distance of 2, 4, 6 and 8 m away from the palm oil waste dumpsite which has been in existences for over 30 years. Thereafter, the soil samples were taken to Biological Sciences Department garden, Kogi state University Anyigba, Nigeria. Ten seeds of Amaranthus hybridus were sown in each of the soil samples. The control soil was without palm oil wastes. Results: Vegetative analysis of the Amaranthus hybridus plants after 2, 4 and 6 weeks of planting revealed significant increase (p<0.05) in plant height, leaf area, stem girth and number of leaf in the plants grown in palm oil wastes soil when compared to control soil. The highest growth performance was at 6 m while the lowest was at control. Phytochemical analysis of the Amaranthus hybridus plants after 2, 4 and 6 weeks of planting revealed significant increase (p<0.05) in the phytochemical constituents at 4, 6 and 8 m and a decrease at 2 m when compared to the control soil. The highest phytochemical constituents occurred at 6 m for tannin saponins and phytate while that of oxalate and flavonoid occurred at 8 m, respectively. Except for phenol, the lowest phytochemical constituents occurred at 2 m. Conclusion: The study therefore concludes that palm oil wastes soil increases the growth and phytochemical constituents of Amaranthus hybridus.