Abstract: In this study, antibacterial activities of some seaweeds from Northern Cyprus against some food-related pathogens were examined. The methanolic extracts of eight seaweeds belonging to Rhodophyceae (Haliptilon attenuatum, Dasya rigidula, Spyridia filamentosa), Phaeophyceae (Cystoseira foeniculacea, Dictyota dichotoma var. intricata) and Chlorophyceae (Caulerpa racemosa, Caulerpa prolifera, Ulva linza) classes collected from North Cyprus (Eastern Mediterranean Sea) during late summer in 2006 and 2007 were studied for their antibacterial activities against some common food-borne pathogens species: Staphylococcus aureus, Salmonella Typhimurium (S. enterica subsp. enterica), Escherichia coli O157:H7, Aeromonas hydrophila and Yersinia enterocolitica, in vitro. S. aureus was the most sensitive bacterium since it was inhibited by most of the extracts. On the other hand, A. hydrophila was not inhibited by any of the extracts. The greatest inhibitory activity against Salmonella Typhimurium was shown by C. foeniculacea extract. Most of the extracts inhibited the growth of E. coli O157:H7. The C. foeniculacea extract also showed the broadest inhibitor activity against food-related pathogens. Six species (D. rigidula, S. filamentosa, C. foeniculacea, D. dichotoma var. intricata, C. racemosa and C. prolifera) were shown inhibitor activity against food-related pathogens.