Abstract: The aim of this study is to determine the antimicrobial activity of Cinnamomum verum stem bark aqueous extract against food-borne pathogen bacteria, nosocomial infection bacteria and normal flora. Extraction with an aqueous system from the dried stem barks of C. verum yielded 2.5% of the dried plant. Among 10 test strains of bacteria, C. verum showed inhibitory effect on the growth of Krebsilla pneumoniae ATCC 10031, Straphylococcus epidermidis ATCC 12228 and E.coli ATCC 25922 in an agar diffusion test. The Minimal Inhibitory Concentrations (MICs) and the Minimal Bactericidal Concentrations (MBCs) were in the range of 4-16 and 16-32 g L-1, respectively. In conclusion, C. verum stem bark aqueous extract showed interesting inhibitory effect on the growth of S. epidermidis, K. pneumoniae and E. coli at low minimum concentration. This may give additional information of antimicrobial activity of C. verum stem bark aqueous extract.