Abstract: Phytochemical screening of aqueous root extract of Leptadenia hastata was investigated in Maiduguri northern Nigeria, to evaluate the active component of the plant. Soxhlet extraction method was used to determine the phytochemical component of the extract. Saponins and flavonoids had high scores in the extract, alkaloids and pentoses had moderate scores, while tannins and ketones had low scores. Combined anthraquinones, free anthraquinones, reducing sugar, carbohydrates, glycosides and monosaccharides were not detected in the extract. In conclusion, Leptadenia hastata aqueous root extract contains pharmacologically active components which support its Ethno-botanical claims of traditional herbalist in Northern Nigeria in the treatment of various ailments.