Abstract: Background and Objective: Over the years poultry producers have relied on the use of antibiotics as growth promoters to improve the performance and the health status of their birds. This study was conducted to test the effect of 'chicken protector' a combination of prebiotics and phytobiotics on the immunological, haematological and bacteriological status of broilers for 21 days. Materials and Methods: In the experiment, 50 Cobb 500 one-day old broiler chicks obtained from a local hatchery in Ghana were used. They were randomly assigned to two treatments, chicken protector (T1) and control (T2) in a Completely Randomized Design (CDR) for 21 days. The parameters that were measured included, haematological parameters, body weight, blood cholesterol levels, immunology, histological performance and gut microbial level. Results: The inclusion of the chicken protector in the water of broiler chicks significantly reduced blood cholesterol levels on day 7 and day 14 (p<0.05). White blood cell count, red blood cell, haematocrits, neutrophils and platelet large cell ratio were all significantly improved at day 7 with the inclusion of the chicken protector. The chicken protector was effective in reducing cholesterol levels in the blood on days 7 and 14 but no significant difference was seen on day 21. Conclusion: Despite the improvement in the haematological parameters of broilers, the inclusion of the chicken protector did not improve the body weight gain of the broiler chickens compared to the control group. Per the results obtained from the study, prebiotics can serve as an alternative for antibiotic usage in broiler production but benefits can best be determined when broilers are grown to the end of production.