Abstract: The present study was planned to evaluate the effects of turmeric (Curcuma longa) for protection against alterations resulted from exposure to endosulfan in broiler chicks. A total of 180 day old chicks were divided into 6 groups of 30 chicks with 3 replicates. First group was fed basal diet while the other five groups were fed basal diet supplemented with 5 g turmeric, 10 g turmeric, 30 mg endosulfan, 30 mg endosulfan plus 5 g turmeric and 30 mg endosulfan plus 10 g turmeric/kg diet during the experimental period. Growth performance, carcass traits, blood parameters, oxidative status and viability of the broilers chicks were used as criteria of response. The results showed that endosulfan significantly decreased the levels of Total Protein (TP), albumin (ALB), globulin (GLB), HDL-cholesterol, catalase (CAT), superoxide dismutase (SOD) activity and reduced glutathione (GSH) concentration but significantly increased albumin/globulin (A/G) ratio, total cholesterol (TCHO), LDL-cholesterol, triglyceride (TRG), malondialdehyde (MDA) concentration and hepatic transaminases (alanine amino-transferase, ALT and aspartate amino-transferase, AST) and exhibited different alterations to the hepatic structure in comparison with control and both turmeric groups. Dietary supplementation of turmeric at different levels could ameliorate these effects but not restored to control level. It is recommended that regular consumption of turmeric in the diet of broiler chicks provides a constant supply of potential antioxidants that could reduce these alterations.