Abstract: An experiment was carried out to evaluate the effect of different dietary protein (CP) levels (24, 22 and 20%) with or without enzyme addition on growth performance of Japanese Quail. At two weeks old, quail were randomly distributed into six experimental groups, each with three equal replications and fed their respective experimental diets and managed similarly. The criteria of response were growth performance (live body weight, weight gain, feed intake, feed conversion ratio and crude protein intake), nutrient digestibility, some carcass traits and blood parameters (total protein, total lipids and total cholesterol, ALT and AST). Apart from the effect of dietary enzyme supplementation, decreasing dietary CP level from 24-20% caused significant reductions in growth performance (live body weight, weight gain, crude protein intake and feed conversion ratio) of quail. Added exogenous enzyme achieved beneficial effects on quail growth performance but feed intake was unaffected compared with the controls, regardless of the effect of dietary protein level. Nutrient digestibility coefficients were significantly depressed when dietary CP level was decreased from 24-20% but added exogenous enzyme produced positive effects on digestibility of nutrients examined. Neither dietary protein level nor enzyme addition had an effect on carcass traits or blood parameters of quail. It can be concluded that an optimal dietary crude protein level for growing Japanese quail is 24% from 14-42 days of age. Added exogenous enzyme is suggested to have a positive effect on growth performance of quail fed the low protein diets.