Abstract: El Niño influences the climate over a broad region in the world and could shift the oceanic upwelling. The intensity of the upwelling at the northern coast of Gulf of Guinea (GG) is characterized by strong year-to-year variability with anomalous warming events that reach 1 or 2°C some years but how this event responds to natural climate-driven change in the physical environment still remains not well understood. The Sea Surface Temperature (SST) from the Reynolds datasets of the last 3 decades (1982-2010) was analyzed to evaluate the long term variability of the coastal upwelling in July-September of the northern Gulf of Guinea and the influence of El Niño-Southern Oscillation (ENSO) on this phenomenon. This major coastal upwelling of GG is important for the marine ecosystem and the fishery. It also influences the precipitation of the bordering countries. Lag relationship of 7-8 and 18 months was observed between the peaks of the strong El Niño (La Niña) events in the Pacific Ocean and the strongest warming (cooling) during summer at the northern coast of GG. Particularly, the strong cooling in July-September at the northern coast of GG occurred one year after the strong La Niña events in the Pacific Ocean. These results suggest that El Niño or La Niña events lead the SST variability at the northern coat of GG.