In ancient times herbal plants have been using as traditional medicine as they are incredible sources of biologically active compounds with therapeutic properties. Though herbal plants play a vital role in prevention and treatment, diverse groups of people were using herbal plants for the treatment of various human diseases. Globally, several plants of various ethnicities have been associated with the development of human civilization. However, phytochemical ingredients within plants increase the medicinal value of it. Recently, the conceivable source for the development of new herbal drugs is known to be medicinal plants as they possess immense healing properties. In the 21st century, the management of healthcare against various emerging diseases is a real big challenge. Therapeutic effects of medicinal plants act as convivial for optimistic future medicine. In recent years, there has been a renaissance of interest to rediscover the potential of medicinal plants as a source of medicament. Moreover, aquatic plants are considered a menace as they are often resulting in eutrophication but this is also an illusion. Many aquatic plants are precious for mankind as they possess alleviating properties that are worth mentioning for several years. Therefore, the present review aims to understand the therapeutical properties of selected aquatic plants (Lemna minor L., Hydrilla verticillata L., Ceretophyllum demesrum L. Ipomea aquatica, Salviia minima L.) as a future source of herbal drugs.