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Trends in Medical Research
  Year: 2017 | Volume: 12 | Issue: 2 | Page No.: 71-76
DOI: 10.3923/tmr.2017.71.76
 
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Comparison of Analgesia Duration of Different Epidural Bupivacaine Volume for Lower Extremities Orthopedic Surgery
Syamsul Hilal Salam , Mohammad Reza Noor, Syafruddin Gaus, Syafri Kamsul Arif and Andi Husni Tanra

Abstract:
Background and Objective: Epidural analgesia is a technique of choice for reduction of acute pain due to surgery of the lower limb. This study aimed to compare the time of administration and side effects of intermittent bolus of bupivacaine 0.125% of volume 6, 8 and 10 mL in lower extremities procedure under epidural analgesia. Materials and Methods: This study was a single blind clinical experimental test. Samples were patients with 18-64 years of age, clinical criteria ASA PS I-II undergoing elective surgery of the lower limb. Randomization was done to obtain three groups with a sample size of 20 patients in each research group. The three groups were given a bolus of bupivacaine 0.125% 6, 8 and 10 mL, respectively. Data obtained were analyzed with one-way ANOVA and SPSS. Statistical analysis was done by using unpaired t-test, Chi-Square test and p<0.05 was considered significant. Results: Observation and recording time of onset of pain relief using numeric rating scale (NRS), with target of NRS<3 (mild pain). Pain relief of using 0.125% bupivacaine bolus increase as dose increase and the incidence of adverse events arising subsequently recorded. The time duration of intermittent bolus administration was shorter in 6 mL group (3 h, 50 min) than in 8 mL group (4 h, 56 min) and 10 mL (5 h, 17 min). Statistically, there was no significant difference between 8 and 10 mL group. Side effects were more common in the group of 10 mL compared to the 6 mL group and 8 mL group. Conclusion: It was concluded that administration of 8 mL, 0.125% bupivacaine has a better effect than 6 and 10 mL. The greater the volume that is used the greater the side effects that could occur.
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How to cite this article:

Syamsul Hilal Salam, Mohammad Reza Noor, Syafruddin Gaus, Syafri Kamsul Arif and Andi Husni Tanra, 2017. Comparison of Analgesia Duration of Different Epidural Bupivacaine Volume for Lower Extremities Orthopedic Surgery. Trends in Medical Research, 12: 71-76.

DOI: 10.3923/tmr.2017.71.76

URL: https://scialert.net/abstract/?doi=tmr.2017.71.76

 
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