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Trends in Medical Research
  Year: 2017 | Volume: 12 | Issue: 1 | Page No.: 26-31
DOI: 10.3923/tmr.2017.26.31
Levels of Trace Elements and Antioxidant Vitamins in Type 2 Diabetic Patients in Ile-Ife, Nigeria
O.F. Fagbohun, B. O. Emma-Okon, F. K. Agboola, B. A. Kolawole, O. H. Onakpoya and T.O. Odewole

Abstract:
Background: Levels of Zn, Cu, Mg, vitamin E and vitamin C were measured in 65 Nigerian diabetic subjects with and without micro vascular complications and compared with controls, in order to ascertain their association with the disease and its complications. Methods: Fasting blood glucose, glycated hemoglobin, Zn, Cu, Mg, vitamin E and vitamin C were assayed according to standard procedures. Statistical analysis was carried out using SPSS version 17.0. Results: Mean values of Zn, Mg and vitamin E were significantly higher (p<0.05) in control groups than diabetic subjects. The Zn levels correlated negatively with fasting blood glucose (p = 0.000, R = -0.443) and glycated hemoglobin (p = 0.030, R = -0.269) while Mg and vitamin E correlated negatively with fasting blood glucose (p = 0.000. R = -0.405 and p = 0.000, R = -0.524, respectively). The Zn, Mg and vitamin E levels correlated positively with each other. Diabetic subjects with retinopathy and nephropathy had significantly lower levels of vitamin E than others. Conclusion: Alterations in trace elements and vitamin status were observed in Nigerian diabetes mellitus subjects. The pattern differs from previous studies in respect of Cu and vitamin C levels. The alterations appear to be more as a result of diabetes itself, rather than being involved in the progression of the disease.
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How to cite this article:

O.F. Fagbohun, B. O. Emma-Okon, F. K. Agboola, B. A. Kolawole, O. H. Onakpoya and T.O. Odewole, 2017. Levels of Trace Elements and Antioxidant Vitamins in Type 2 Diabetic Patients in Ile-Ife, Nigeria. Trends in Medical Research, 12: 26-31.

DOI: 10.3923/tmr.2017.26.31

URL: https://scialert.net/abstract/?doi=tmr.2017.26.31

 
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