|
|
| |
| Prevalence of Haemoglobin Variants, ABO and Rhesus Blood Groups in Ladoke Akintola University of Technology, Ogbomoso, Nigeria |
|
R.E. Akhigbe,
S.F. Ige,
A.O. Afolabi,
O.M. Azeez,
G.J. Adegunlola and J.O. Bamidele |
Abstract:
In view of the association of various haemoglobin genotypes
and blood groups with different pathological conditions and the risk of
alloimmunization from allogeneic blood transfusion seen in patients with
sickle cell disease, the incidence of haemoglobin variants, ABO and Rhesus
(Rh) blood groups in Ladoke Akintola University of Technology (LAUTECH),
Nigeria, was assessed. This is a retrospective study using medical records
of 1122 students (between 18-25 years old) of LAUTECH. Out of the 1122
students, 71.03% were HbAA, 22.19% HbAS, 5.26% HbAC, 0.54% HbSS, 0.80%
HbSC and 0.18% HbCC. No incidence of HbSS, HbSC and HbCC in male. The
frequencies of A, B, AB and O blood groups were 21.30, 22.73, 2.85 and
53.12%, respectively. The 93.32% were Rhesus positive (Rh+),
while the remaining 6.68% were Rhesus negative (Rh¯). Results from
this study show a low prevalence of abnormal haemoglobin variants. Blood
group O was most predominant, while blood group AB was least dominant.
In conclusion, this study shows that there is a decline in the prevalence
of haemoglobinopathies in the studied area. Also, routine haemolysin test
should be conducted on every group O blood before blood transfusion to
reduce the risk of transfusion reaction since some group O blood, which
is the predominant blood group, is known to contain immune haemolytic
antibodies.
|
|
|
[Fulltext
PDF]
[Fulltext
HTML] [XML: Abstract + References]
[References]
[View
Citation]
[Report
Citation]
|
|
|
|
| RELATED ARTICLES: |
|
|
|
How to cite this article:
R.E. Akhigbe, S.F. Ige, A.O. Afolabi, O.M. Azeez, G.J. Adegunlola and J.O. Bamidele, 2009. Prevalence of Haemoglobin Variants, ABO and Rhesus Blood Groups in Ladoke Akintola University of Technology, Ogbomoso, Nigeria. Trends in Medical Research, 4: 24-29.
DOI: 10.3923/tmr.2009.24.29
URL: https://scialert.net/abstract/?doi=tmr.2009.24.29
|
|
|
| |
| COMMENT ON THIS PAPER |
|
|
|
|
| |
 |
Navigation |
| |
|
|
| |
|
Indexed In |
| |
|
|
Subscribe Today 
