Some Lysosomal Enzyme Profiles in Children with Nephroblastoma: The Effect of Nephrectomy


	Trends in Medical Research
	Year: 2007 \| Volume: 2 \| Issue: 1 \| Page No.: 51-56 DOI: 10.3923/tmr.2007.51.56

Some Lysosomal Enzyme Profiles in Children with Nephroblastoma: The Effect of Nephrectomy

Donatien Gatsing, H. Ibrahim Garba , Roseline Aliyu , H. Abiodun Adebayo , P. Obekpa and I. Godwin Adoga

Abstract: The serum levels of some lysosomal enzymes-namely β-glucuronidase (EC 3.2.1.31), β-galactosidase (EC 3.2.1.23) and acid phosphatase (EC 3.1.3.2)-were measured in controls, pre-operative and post-operative nephroblastoma patients. β-glucuronidase activity showed a significant (p<0.05) increase before surgical intervention, followed by significant (p<0.05) decreases 24 h, 72 h and 7 days after operation. The activities of β-galactosidase and acid phosphatase showed no significant (p>0.05) changes before and after surgical intervention. These data indicate that nephroblastoma and surgery may have a marked effect on the serum levels of some lysosomal enzymes.

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How to cite this article:

Donatien Gatsing, H. Ibrahim Garba , Roseline Aliyu , H. Abiodun Adebayo , P. Obekpa and I. Godwin Adoga , 2007. Some Lysosomal Enzyme Profiles in Children with Nephroblastoma: The Effect of Nephrectomy. Trends in Medical Research, 2: 51-56.

DOI: 10.3923/tmr.2007.51.56

URL: https://scialert.net/abstract/?doi=tmr.2007.51.56

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