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Trends in Medical Research
  Year: 2007 | Volume: 2 | Issue: 2 | Page No.: 102-107
DOI: 10.3923/tmr.2007.102.107
 
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Evaluation of a New Urinary Bladder Tumor Marker in Comparison with Cytology for Rapid Diagnosis of Bladder TCC

Sohair Aly Hassan and Mahmoud El-Sherbiny

Abstract:
A new Bladder Tumor Marker has been developed to detect early TCC bladder cancer. Objective to evaluate the Bladder Tumor Marker (BTM) as a new developed tumor marker in comparison to cytology. Transurethral specimens and voided urine samples were collected from 30 patients with haematuria selected from inpatients of Theodur Bilharz Institute-Cairo. The samples were diagnosed according to histopathological examination into 25 samples with TCC, 5 samples were served as control since they were complains of no cancerous symptoms and were suffering from other genitourinary pains. Urine samples were tested by BTM and cytology. The results were correlated with the final diagnosis (histopathology) and with tumor grade and stage. Sensitivity of BTM test was 72% and specificity was 60%. The corresponding cytology results were 44 and 100%, respectively. BTM was highly sensitive in grade I and stage I, 86 and 89% in comparison to 57 and 33% in cytology. Cytology appeared to be highly sensitive in grade III compared to BTM, 80 and 60%, respectively. BTM is more sensitive and valuable in detecting low grade and stage compared to cytology for early detection of TCC bladder tumor.
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How to cite this article:

Sohair Aly Hassan and Mahmoud El-Sherbiny , 2007. Evaluation of a New Urinary Bladder Tumor Marker in Comparison with Cytology for Rapid Diagnosis of Bladder TCC. Trends in Medical Research, 2: 102-107.

DOI: 10.3923/tmr.2007.102.107

URL: https://scialert.net/abstract/?doi=tmr.2007.102.107

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