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Trends in Applied Sciences Research
  Year: 2012 | Volume: 7 | Issue: 9 | Page No.: 748-757
DOI: 10.3923/tasr.2012.748.757
 
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Estimating the Plasma and Serum Activity Levels of Aspartate Aminotransferase and Alanine Aminotransferase, in Live Animals Using Regression Model
V.M. Ahur, P.O. Agada and S.A. Saganuwan

Abstract:
There is a challenge in estimating the plasma/serum activity levels of aspartate aminotransferase (AST) and alanine aminotransferase (ALT) concentrations using continuous absorbance values determined from previous experiments by the Randox Company. Reitman and Frankel determined the activity levels of AST over a discrete range of absorbance values (0.02, 0.17) with a step size of 0.01 and an activity level of ALT over a discrete range of absorbance values (0.025, 0.500) with a step size of 0.025, making the estimation a difficult task. The work provides an AST and ALT absorbance regression models for estimating the plasma/serum activity levels of AST and ALT. The validity of the AST and ALT absorbance regression models is confirmed by their respective values of coefficients of determination (R2) at 99.65 and 99.44% suggesting the reliability of the model. Hence, the model can be used to determine the plasma/serum activity levels of AST and ALT in live animals.
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How to cite this article:

V.M. Ahur, P.O. Agada and S.A. Saganuwan, 2012. Estimating the Plasma and Serum Activity Levels of Aspartate Aminotransferase and Alanine Aminotransferase, in Live Animals Using Regression Model. Trends in Applied Sciences Research, 7: 748-757.

DOI: 10.3923/tasr.2012.748.757

URL: https://scialert.net/abstract/?doi=tasr.2012.748.757

 
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