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Science International
  Year: 2013 | Volume: 1 | Issue: 8 | Page No.: 282-298
DOI: 10.17311/sciintl.2013.282.298
A Biotechnological Approach to Apoptosis in Living Organisms: An Overview
Sanjay Mishra

Background: Living organisms use apoptosis for resistance and progressive mechanisms. A noteworthy commonality has been advocated between the hallmarks of apoptosis in plants and animals, both at cellular and molecular level though very few governing proteins or protein domains have been identified as conserved across all eukaryotic apoptotic forms, biochemical and biotechnological topographies viz., chromatin condensation, nuclear DNA fragmentation and contribution of caspase like proteases in plant apoptosis look like across the board and in conformism with the process in metazoans as well. Transgenic expression of mammalian anti- and pro-apoptotic proteins in plants has been shown to influence the regulatory pathways of cell death processing, indicative of the existence of functional counterparts of such genes in plants, several of which have now been cloned and characterized extensively, suggesting that despite variances, there may be a rational level of functional resemblance between the mechanistic components of apoptosis of biosystems. Results: An overview of the existing data concerning with mechanism of apoptosis in plants is at best inclined to support an inherited association with animal apoptosis rather than any common governing approaches. Conclusion: This overview provides a brief insight into some of the relative features of Programmed Cell Death (PCD) in plants and animals.
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How to cite this article:

Sanjay Mishra , 2013. A Biotechnological Approach to Apoptosis in Living Organisms: An Overview. Science International, 1: 282-298.

DOI: 10.17311/sciintl.2013.282.298






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