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Research Journal of Veterinary Sciences
  Year: 2012 | Volume: 5 | Issue: 3 | Page No.: 59-68
DOI: 10.3923/rjvs.2012.59.68
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Histopathological Effects Induced by Single Dose of Atrazine in Spermatids of Goat in vitro

R.K. Sharma, P.K. Chauhan and A. Fulia

Atrazine, an agricultural pesticide widely used all over the world, has now been recognized as an endocrine disrupting chemical which affects the reproductive system of mammals. The objective of the present study was to analyze the effect of single dose of atrazine on spermatids of Capra hircus in vitro. Small pieces (approximately 1 mm3) of testicular tissue were divided into experimental and control group. The experimental group was treated with atrazine concentration (1.0 nmol mL-1) and exposed for 1, 4 and 8 h. Atrazine, 1.0 nmol mL-1 revealed increasing morphological alterations in spermatids. After 1 h exposure, pycnosis and chromatolysis were observed in few spermatids. Atrazine exposure induced alterations in fine morphology of spermatids, degenerated nuclear membrane and pinching off of the nuclear material was clearly visible. Nanomolar concentration of atrazine has deleterious effects on testicular structure including fine morphology and severely impaired the spermatozoa formation and finally affects the reproductive potential of goat.
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  •    Testicular Histopathological Alterations in Rats Treated with Sumithion® NP 25/2.5 EC, Insecticide
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  •    In vitro Effects of Diazinon on Male Reproductive Tissue and Sperm Motility of Caspian Kutum (Rutilus frisii kutum)
How to cite this article:

R.K. Sharma, P.K. Chauhan and A. Fulia, 2012. Histopathological Effects Induced by Single Dose of Atrazine in Spermatids of Goat in vitro. Research Journal of Veterinary Sciences, 5: 59-68.

DOI: 10.3923/rjvs.2012.59.68






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