Abstract:
The aims of this study were to investigate the effect of high-fat diet feeding for 30 days on Body Weight (BW), Body Fat (BF), Pelvic Circumference (PC), plasma metabolite, hormone and cytokine levels and to demonstrate correlations between BF and biochemical makers in dogs. All subject dogs which were diagnosed clinically healthy and Body Condition Score (BCS) 3 were four female Beagles. All dogs were fed with high-fat diet containing 30% higher calorie compared to the usual diet. At this examine, BF was determined using morphometric measurement with simple calculations and non clinical laboratory equipment. As a result, BUN concentrations decreased significantly and plasma concentrations of adiponectin, as key factor for obesity and insulin resistance, decreased 19%, whereas visfatin increased 11%. BW, BF, PC, glucose, AST, insulin and Cholesterol Ester Transfer Protein (CETP) levels to assess metabolic conditions increased significantly in overweight dogs. Body fat, was calculated by simple formula without specific laboratory equipment, showed strongly positive correlation with plasma ALT, TNF-α and insulin levels and appeared to be a useful indicator to assess physical and metabolic condition of overweight dogs.
N. Mori, M. Sakai, I. Yamamoto and T. Arai, 2011. Alternation of Physical Indexes and Plasma Biochemical Makers in Overweight Dogs Induced by High-Fat Diet Feeding. Research Journal of Veterinary Sciences, 4: 14-19.
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