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Research Journal of Toxins
  Year: 2014 | Volume: 6 | Issue: 1 | Page No.: 1-7
DOI: 10.3923/rjt.2014.1.7
 
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Antimicrobial Properties of Penicillium Species Isolated from Agricultural Soils of Northern Iran

E. Gharaei-Fathabad, M.A. Tajick-Ghanbary and N. Shahrokhi

Abstract:
As a part of a research program that aimed to identify antibacterial and antifungal substances from fungus specimen of North Iranian soil samples, four penicillium species were identified as a source of secondary metabolites possessing antibiotic activities. These microorganisms were cultured in a liquid medium for 10 days. The antimicrobial disc assay activity of these extracts towards Candida albicans, Bacillus subtillis, Staphylococcus aureus, Salmonella typhi and Escherichia coli was performed. Supernatants and cell extracts of P. viridicatum Westling, P. citrinum Thom., P. aurantiogriseum Dierckx and P. waksmanii Zaleski showed distinguished antimicrobial activities. TLC assay of supernatants and cell extracts showed production of citrinin by P. citrinum and P. aurantiogriseum and penicillic acid by P. viridicatum and P. aurantiogriseum; while two unknown metabolites from P. waksmanii needed more examinations. These mycotoxins could be examined for other biological activities such as antineoplastic property.
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How to cite this article:

E. Gharaei-Fathabad, M.A. Tajick-Ghanbary and N. Shahrokhi, 2014. Antimicrobial Properties of Penicillium Species Isolated from Agricultural Soils of Northern Iran. Research Journal of Toxins, 6: 1-7.

DOI: 10.3923/rjt.2014.1.7

URL: https://scialert.net/abstract/?doi=rjt.2014.1.7

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