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Research Journal of Phytochemistry
  Year: 2017 | Volume: 11 | Issue: 1 | Page No.: 11-19
 
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A Comparison of Chemical Composition, Antioxidant and Antimicrobial Studies of Abutilon indicum Leaves and Seeds

K. Radhakrishnan, A. Mohan, Shanmugavadivelu Chandra Mohan and S. Velavan

Abstract:
Objective: The objective of this study was to evaluate in vitro antioxidant, antimicrobial activity and characterize the chemical constituents of leaves and seeds of Abutilon indicum by using gas chromatography-mass spectrometry (GC-MS). In addition total phenolics and flavanoids were also estimated. Materials and Methods: The GC-MS analysis of plant and seed extracts was performed using a GC-Brucker 436 system and interpretation on mass spectrum GC-MS was conducted using the database of National Institute Standard and Technology (NIST). Antioxidant activity was determined in the 1,1-diphenyl-2-picrylhydrazyl (DPPH) method. The total flavonoids assay was conducted by aluminium chloride colorimetric method and otal phenolics content was determined according to the Folin-Ciocalteu method. Antibacterial activity and minimum inhibitory concentrations were calculated by the agar diffusion method. Results: Twenty five chemical compounds are identified from the plant extract and 29 compounds identified from seed extract by GC-MS analysis. The leaf and seed extracts showed significant DPPH scavenging activity (IC50 values are 48.94±3.54 and 49.89±3.29 μg mL–1) compared with the values obtained for ascorbic acid standard (IC50 value 39.22±5.50). The leaf and seed extracts prevented the growth of both Gram-positive and Gram-negative bacteria. The antimicrobial and antioxidant activities of the extracts were positively associated with the total phenolic and flavonoid contents of the extract. Conclusion:The presence of various bioactive compounds justifies the use of Abutilon indicum for various ailments by traditional practitioners.
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How to cite this article:

K. Radhakrishnan, A. Mohan, Shanmugavadivelu Chandra Mohan and S. Velavan, 2017. A Comparison of Chemical Composition, Antioxidant and Antimicrobial Studies of Abutilon indicum Leaves and Seeds. Research Journal of Phytochemistry, 11: 11-19.

URL: https://scialert.net/abstract/?doi=rjphyto.2017.11.19

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