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Research Journal of Phytochemistry
  Year: 2016 | Volume: 10 | Issue: 1 | Page No.: 30-38
DOI: 10.3923/rjphyto.2016.30.38
In vivo Anti-malarial Activity of Cleome viscosa L. Whole Plant
T.O. Elufioye and J.O. Onoja

Abstract:
This study aimed to investigate in vivo anti-malarial effect of methanolic extract of Cleome viscosa whole plant and fractions (n-hexane and ethyl acetate) against early, established and residual malaria infections. The in vivo anti-malarial effect against early infection, curative effect against established infection and prophylactic effect against residual infection were studied in chloroquine-sensitive Plasmodium berghei NK-65 strain infected mice. The results showed that the methanol extract of Cleome viscosa whole plant and partitioned fractions demonstrated significant (p<0.05) dose-dependent anti-malarial activity in all three antimalarial evaluation models thus justifying the inclusion of this plant in recipes for treating malaria.
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How to cite this article:

T.O. Elufioye and J.O. Onoja, 2016. In vivo Anti-malarial Activity of Cleome viscosa L. Whole Plant. Research Journal of Phytochemistry, 10: 30-38.

DOI: 10.3923/rjphyto.2016.30.38

URL: https://scialert.net/abstract/?doi=rjphyto.2016.30.38

 
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