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Research Journal of Phytochemistry
  Year: 2014 | Volume: 8 | Issue: 2 | Page No.: 52-56
 
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Cytotoxic Steroids from the Stem Barks of Pandanus tectorius

N.T. Hoa, P.H. Dien and D.N. Quang

Abstract:
n-Hexane extract of the stem barks of Pandanus tectorius Parkins. ex J. P. du Roi collected in Thuathien-Hue province, Vietnam has shown a good cytotoxicity activity against KB (a human epidermal carcinoma) cell line with the IC50 value of 45.33 μg mL-1. Investigation on the chemical constituents of this extract has resulted in the isolation of four compounds: (a) Stigmast-4-en-3-one, (b) Stigmasta-4,22-dien-3-one, (c) Cycloeucalenol and (d) Stigmast-22-en-3β-ol. Their structures were determined by various spectroscopic methods. In addition, compounds (a-c) were evaluated their cytotoxic activity against KB cell line, compound b has moderate activity (IC50 value of 88.96 μg mL-1).
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How to cite this article:

N.T. Hoa, P.H. Dien and D.N. Quang, 2014. Cytotoxic Steroids from the Stem Barks of Pandanus tectorius . Research Journal of Phytochemistry, 8: 52-56.

URL: https://scialert.net/abstract/?doi=rjphyto.2014.52.56

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