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Research Journal of Phytochemistry
  Year: 2014 | Volume: 8 | Issue: 2 | Page No.: 35-41
DOI: 10.3923/rjphyto.2014.35.41
 
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Antimicrobial and Wound Healing Potential of Canthium coromandelicum Leaf Extract-A Preliminary Study

S. Chandra Mohan, K. Sasikala and T. Anand

Abstract:
The objective of this study was to evaluate the wound healing potential of the ethonolic extract of Canthium coromandelicum. The study was done on male albino rats using excision model. The ethanolic extract, treated wounds were found to epithelize faster and the rate of wound contraction was significantly increased as compared to control and standard wounds (p<0.001and p<0.01). From the results, the ethanolic extract of Canthium coromandelicum had greater wound healing activity than the standard ointment Cipladine. The enhanced wound healing activity of alcoholic extract may be due to free radical scavenging action and the antibacterial property of the phyto constituents (viz., tannins and flavonoids) present in it which either due to their individual or additive effect fastens the process of wound healing. Presence of flavonoids and tannins in alcohol extract was also confirmed by preliminary phytochemical investigation.
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How to cite this article:

S. Chandra Mohan, K. Sasikala and T. Anand, 2014. Antimicrobial and Wound Healing Potential of Canthium coromandelicum Leaf Extract-A Preliminary Study. Research Journal of Phytochemistry, 8: 35-41.

DOI: 10.3923/rjphyto.2014.35.41

URL: https://scialert.net/abstract/?doi=rjphyto.2014.35.41

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