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Research Journal of Phytochemistry
  Year: 2013 | Volume: 7 | Issue: 1 | Page No.: 1-9
 
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Two Cinnamoyl Triterpenes and Steroids from Crotalaria incana (Fabaceae)

A.T.M. Zafrul Azam, Fatema Moni, Md. Hamiduzzaman, Mohammad Mehedi Masud and Choudhury Mahmood Hasan

Abstract:
Crotalaria incana (L.) is an important medicinal plant in Bangladesh. Its traditional uses have a great appeal locally and specially to the tribal people in the hilly area of country. Its folk medicinal uses reflect the presence of medicinally important secondary metabolites of great interest. In order to explore the possibilities of developing new drug molecules from the investigated plant, it was subjected to phytochemical screening. So the present study has reported the isolation and characterization of two steroids and two cinnamoyl triterpenes from the leaves of C. incana (family-Fabaceae) based on different separation techniques and 1H-NMR data. Reported compounds (1) β-stigmasterol, (2) β-sitosterol, (3) (3β)-(4-hydroxy-E-cinnamoyl)olean-5,12-dien-28-ol and (4) (3β)-(2,3,4-trihydroxy-Z-cinnamoyl)olean-5-ene-12,28-diol were isolated from the petroleum ether soluble fraction of crude methanol extract of leaves of C. incana by combination of column chromatography and preparative thin layer chromatography over silica gel (60H). The structures of these compounds were determined by 1H-NMR spectroscopic method and comparing with published data. This is the first report of isolation of compound 3 and 4 from this plant.
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How to cite this article:

A.T.M. Zafrul Azam, Fatema Moni, Md. Hamiduzzaman, Mohammad Mehedi Masud and Choudhury Mahmood Hasan, 2013. Two Cinnamoyl Triterpenes and Steroids from Crotalaria incana (Fabaceae). Research Journal of Phytochemistry, 7: 1-9.

URL: https://scialert.net/abstract/?doi=rjphyto.2013.1.9

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