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Research Journal of Phytochemistry
  Year: 2011 | Volume: 5 | Issue: 1 | Page No.: 41-47
 
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Head Space GC/MS Analysis of Volatile Constituents of Trichilea connaroides Wight and Arn. Extracts and their in vitro Anti- Plasmodium Activity Against Plasmodium falciparum Isolates

Ravendra Kumar, Gaurav Verma, Om Prakash and A.K. Pant

Abstract:
Head space GC-MS analysis ethyl acetate extracts of leaves, bark, root and pericarps of Trichilia connnaroides Wight and Arn. Revealed the presence of over 45 compounds of which 22.06, 97.24, 46.42 and 58.27% of the total volatiles from extracts of leaves bark, root and pericarps were identified, respectively. The volatile constituents of bark extract were rich in sesquiterpenoides. Copaene (24.71%), azulene (17.47%), α-cubebene (14.98%), β-cadinene (12.58%), α-bergamotene (4.96%) and ylangene (5.50%) were the major constituents of the total volatiles of the extract. The identified constituents in other extract were 22.06% in leaves extract, 46.42% in root extract and 58.26% in pericarp extract, respectively. In vitro antiplasmodium activity of five extract were tested against K 1 strain of Plasmodium falciparum isolates. All the extract showed antiplasmodial activity. Relatively high activity was observed in dichloromethane extract.
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How to cite this article:

Ravendra Kumar, Gaurav Verma, Om Prakash and A.K. Pant, 2011. Head Space GC/MS Analysis of Volatile Constituents of Trichilea connaroides Wight and Arn. Extracts and their in vitro Anti- Plasmodium Activity Against Plasmodium falciparum Isolates. Research Journal of Phytochemistry, 5: 41-47.

URL: https://scialert.net/abstract/?doi=rjphyto.2011.41.47

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