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Research Journal of Phytochemistry
  Year: 2009 | Volume: 3 | Issue: 4 | Page No.: 68-76
DOI: 10.3923/rjphyto.2009.68.76
In vitro Investigation of Antioxidant Phenolic Compounds in Extracts of Senna alata
J. Okpuzor, H. Ogbunugafor, G.K. Kareem and M.N. Igwo-Ezikpe

Abstract:
Extracts of Senna alata were investigated for antioxidant phenolic compounds using High Performance Liquid Chromatography (HPLC). The dried aerial plant parts were macerated into powder and extracted in different organic solvent systems consisting of methanol, hexane, chloroform, ethyl acetate, butanol and water. Each extract was dried under reduced pressure using a rotary evaporator, freeze-dried and stored at a temperature of 4°C. The extracts were then subjected to high performance liquid chromatography studies. Two major phenolic compounds Naringin and Apigenin, were identified in some of the fractions of Senna alata. The presence of these flavoniods in Senna alata may explain its wide use in ethnomedicine practice for the treatment of hypertension, sickle cell anemia and diabetes in Southwestern Nigeria.
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How to cite this article:

J. Okpuzor, H. Ogbunugafor, G.K. Kareem and M.N. Igwo-Ezikpe, 2009. In vitro Investigation of Antioxidant Phenolic Compounds in Extracts of Senna alata. Research Journal of Phytochemistry, 3: 68-76.

DOI: 10.3923/rjphyto.2009.68.76

URL: https://scialert.net/abstract/?doi=rjphyto.2009.68.76

 
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