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Research Journal of Phytochemistry
  Year: 2009 | Volume: 3 | Issue: 1 | Page No.: 13-17
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Phytotoxic and Chemical Investigations of a Nigerian Medicinal Plant

A. Falodun, A.M.A. Chaudhry and I.M. Choudhary

Pyrenacantha staudtii is a medicinal plant endemic in Nigeria and used ethnomedicinally for the treatment of various diseases by the populace. In continuation of the studies on chemical constituents of Pyrenacantha staudtii, the study was aimed at validating the phytotoxic activity of the leaf extract and through a systematic chemical procedure, isolation and identification of the chemical principles of Pyrenacantha staudtii leaf was established. The investigation of the chemical constituents of Pyrenacantha staudtii leaves has led to the isolation and characterization of two known compounds oleanilic acid and β-amyrin. The compounds were isolated first time from P. staudtii. The structures of the compounds were established by spectral (MS and NMR) and chemical methods. The methanolic extract of P. staudtii exhibited significant phytotoxic activity against Lemna minor L. at 10 μg mL−1. The result of the study has justified the phytotoxic potential of the plant.
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How to cite this article:

A. Falodun, A.M.A. Chaudhry and I.M. Choudhary, 2009. Phytotoxic and Chemical Investigations of a Nigerian Medicinal Plant. Research Journal of Phytochemistry, 3: 13-17.




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