Subscribe Now Subscribe Today
Science Alert
 
Blue
   
Curve Top
Research Journal of Nanoscience and Nanotechnology
  Year: 2015 | Volume: 5 | Issue: 1 | Page No.: 16-26
DOI: 10.3923/rjnn.2015.16.26
 
Facebook Twitter Digg Reddit Linkedin StumbleUpon E-mail

Anti-Angiogenic, Cytotoxic and Antimicrobial Activity of Plant Mediated Silver Nano Particle from Tragia involucrata

M. Manjunath Hullikere, Chandrashekhar G. Joshi, R. Vijay, D. Ananda and M.T. Nivya

Abstract:
The biosynthesis of silver nanoparticles is a cost effective and environmental friendly alternative to chemical and physical methods. In the present study, we have studied the green synthesis of silver nanoparticles from T. involucrata leaf extract and their biological properties. Silver nano particles (AgNPs) were characterized using UV-Visible spectrophotometer (UV-VIS), scanning electron microscope, X-ray diffraction (XRD), fourier transform infrared spectroscopy (FTIR). The AgNPs were tested for cytotoxic, antiangiogenic, antimicrobial as well as DNA diffusion assays. These biogenic nanoparticles showed significant cytotoxic activity against MOLT-4 cell lines, antiangiogenic and antimicrobial activity. Diffusion of DNA was comparatively higher in AgNPs treated cells than the control. Hence, T. involucrata leaf extract mediated AgNPs can be exploited in the development of novel drug. The unique properties of this AgNPs can be put to great use for human betterment.
PDF Fulltext XML References Citation Report Citation
 RELATED ARTICLES:
  •    Antitumor Activity of Hexane and Ethyl Acetate Extracts of Tragia involucrata
  •    Antifertility Activity of Hexane and Ethyl Acetate Extracts of Aerial Parts of Tragia involucrata. Linn
How to cite this article:

M. Manjunath Hullikere, Chandrashekhar G. Joshi, R. Vijay, D. Ananda and M.T. Nivya, 2015. Anti-Angiogenic, Cytotoxic and Antimicrobial Activity of Plant Mediated Silver Nano Particle from Tragia involucrata. Research Journal of Nanoscience and Nanotechnology, 5: 16-26.

DOI: 10.3923/rjnn.2015.16.26

URL: https://scialert.net/abstract/?doi=rjnn.2015.16.26

COMMENT ON THIS PAPER
 
 
 

 

 
 
 
 
 
 
 
 
 

 
 
 
 
 
 

Curve Bottom